by Created on: April 05, 2011 Last Updated: April 06, 2011
Lupus or systemic lupus erythematosus is an autoimmune disease that commonly affects women more than men (9:1). It is caused by hereditary factors and it is categorized as a multigenic disease. In addition, it affects almost every organ system of the body.
What are the significant Lupus symptoms?
Since lupus affects almost all the body organs, women can get wide variety of symptoms. However, only few of these symptoms occur commonly and some of them are used as diagnostic criteria.
GA_googleFillSlotWithSize(HELAD_publishercode, "ArticleATFMiddleArticle300x250", 300, 250);
What are the symptoms that are included in diagnostic criteria?
According to the American college of rheumatology revised criteria for the classification of systemic lupus erythematosus, (Arthritis & Rheumatism 40, 9, 1725, 1997) at least three of the following criteria must be present to diagnose lupus.
1. Malar rash: - It is a red elevated rash situated on check bone of the face.
2. Discoid rash: - It is a Round, red rash that can appear anywhere in the body.
3. Photosensitivity: - Increased sensitivity to light that can cause rashes.
4. Oral ulcers: - Ulcers that occur inside the mouth and nose. It should be assessed by a doctor.
5. Arthritis: - Painful arthritis that is seen at least in two peripheral joints. In addition, affected joints are swollen and contain a fluid.
6. Serositis: - Pluritis (inflammation of the lung pleural membrane) or inflammation of the membranes covering the heart (pericarditis). It can be detected by ECG or chest X ray examination. In addition, women with Pluritis will have chest pain increasing with breathing and shortness of breath due to fluid accumulation inside the lungs. Women with pericarditis may complain chest pain radiating to the left arm, tiredness and shortness of breath.
7. Renal disorder: - Kidney problem is detected by the presence of protein in the urine or cellular casts in the urine. Some women with renal problems can get body swelling and reduced urine output.
8. Seizures or psychosis: - Women with lupus can get seizures that cannot be attributed to any other causes. In addition, they can get symptoms of psychosis such as hallucinations and delusions.
What are the other common symptoms that can occur in women with Lupus?
Most women can get unexplained fatigue, malaise, fever, anemia and weight loss. In addition, hand and bone deformities and muscle pains can occur. Another much more common and annoying symptom is alopecia or hair loss. Additionally, some women can get mood problems with Lupus (Harrison 17th CH313).
Systemic lupus erythematosus is a troublesome and serious autoimmune disorder that can affect women. Most common symptoms that can be seen are fatigue, malaise, rashes and arthritis.
Arthritis & Rheumatism
Harrison’s principles of internal medicine 17th edition
Learn more about this author, .
Click here to send this author comments or questions.